The Cannondale Synapse 2 Road Bike (2025) is a versatile endurance bike designed for comfort and all-round road performance. Its lightweight SmartForm C2 alloy frame and full carbon fork deliver a smooth, responsive ride, while Shimanos new CUES U6000 road group provides durable, precise 2×10-speed shifting and powerful hydraulic disc braking.

Equipped with DT Swiss R 470 DB rims and Vittoria 700x30c tyres for dependable grip and speed, plus Cannondales integrated Wheel Sensor for ride tracking and service reminders, the Synapse 2 road bike is perfect for riders seeking enjoyable, confident road adventures.

Highlights

• Lightweight SmartForm C2 Alloy frame w/ full carbon fork
• Durable, reliable, wide-range, 2×10-speed shifting from Shimanos new CUES U6000 road group
• Powerful, controllable braking from Shimanos CUES hydraulic disc brakes
• Proven all-around road performance from DT Swiss R 470 DB rims with Vittoria 700x30c tires

SPECIFICATIONS

Platform Synapse Model Name Synapse 2 Model Code C12104U Frameset Frame Synapse, lightweight SmartForm C2 Alloy, SmartSense compatible, BSA threaded BB, internal cable routing, flat mount, 142×12 thru-axle, removable fender bridge, hidden rack/fender mounts. Fork Synapse Carbon, integrated crown race, 12x100mm thru-axle, internal routing, flat mount brake, fender mounts. Headset Integrated, 1-1/8″ – 1-1/4″. Drivetrain Rear Derailleur Shimano CUES U6020. Front Derailleur Shimano CUES U6030. Shifters Shimano CUES U6030, 10-speed. Chain Shimano LG500, 10-speed. Crank Shimano CUES 6040, 46/32. Rear Cogs Shimano CUES LG300, 11-39, 10-speed. Bottom Bracket Shimano RS500. Brakes Brakes Shimano CUES hydraulic disc, 160/160mm RT64 rotors. Brake Levers Shimano CUES hydraulic disc. Wheels Front Hub Formula CL-712, 12x100mm centerlock. Rear Hub Formula RXC-400, 12x142mm centerlock. Rims DT Swiss R470 DB, 28h, tubeless compatible. Spokes Stainless Steel, 14g. Tire Size 30. Wheel Size 700c. Tires Zaffiro Pro Bright Black Reflective, 700x30c. Front Tire Vittoria Zaffiro Pro V, 700x30c, reflective strip. Rear Tire Vittoria Zaffiro Pro V, 700x30c, reflective strip. Components Handlebar Cannondale 3, 6061 Alloy, Compact. Stem Cannondale 3, 6061 Alloy, 31.8, 7. Grips Cannondale Bar Tape, 3.5mm. Saddle Fizik Aliante Delta, S-alloy rails. Seatpost Cannondale 3, 6061 Alloy, 27.2x350mm. Extra Extra 1 Trainer axle end caps.